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Healthy Blog » Blog Archive » What Is 5 HTP (5-Hydroxytryptophan)?
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What Is 5 HTP (5-Hydroxytryptophan)?

7 June 2009 One Comment

5-HTP is a safe and effective natural solution for serotonin deficiency and it's related symptoms including - depression, insomnia and obesity.


Are you depressed, anxious; suffer with insomnia, obsessive/compulsive disorders, stress or PMT? Well the answer may be to boost up your serotonin levels. Read on to find out more.


Serotonin is a neurotransmitter or brain chemical that produces an inhibitory effect on the nervous system, which soothes, calms and creates a feeling of contentment. Serotonin has been known to researchers for nearly half a century and new research continues to demonstrate how it influences mood, addictions and emotion. Depression, insomnia, anxiety, suicide, migraines, PMS, obsessive/compulsive behaviour, stress, obesity and addiction can all be manifestations of low levels of serotonin. Since serotonin is found in the brain and central nervous system, it has many implications on mood, behaviour and sleep patterns. It is also found in the blood platelets and some mucosa cells of the gastrointestinal tract.


Depression results, in part, from the lack of serotonin. The leading antidepressants are selective serotonin reuptake inhibitors. By blocking the reuptake of serotonin, they increase the serotonin available to stimulate serotonin receptors. These include Prozac, Zoloft, Paxil, and Effexor. While they may be very effective for the treatment of depression, they are not without side effects, including a loss of sex drive. They are also only available by prescription.


Nature to the rescue!


5 HTP (5-Hydroxytryptophan) is a safe and natural alternative to many antidepressant drugs. Extracted from the seed of griffonia simplicifolia, 5-htp is the immediate metabolite between the amino acid L-tryptophan and the brain chemical serotonin.


Luckily, clinical studies have been done with 5 HTP, comparing their effectiveness to anti depressant drugs. The results of the studies were astounding. Using the standard depression scale, both the drug and 5-HTP groups displayed identical reduction in depression. Depressed patients, who received 100 mg of 5-HTP three times daily, showed at least a 50% improvement in their symptoms, without any reported side effects. Similar studies with depressed children demonstrated equal benefit. Beta-endorphins, the “feel-good” hormones, were also significantly elevated after consumption of 200 mg of 5-HTP by patients with severe depression.


Subsequent studies were performed using 5-HTP for anxiety, panic disorder, sleep difficulties and obesity. Professor Dr R.S. Kahn observed an obvious decline in anxiety symptoms when supplementing with 5-HTP, and patients with panic disorder noticed a feeling of relief after receiving 5-htp. Melatonin, which helps regulate our sleep-wake cycle, is a metabolite of serotonin. Early research studies show that supplementing with 5-HTP can have positive effects on sleep patterns in some people. In another clinical study with obese patients, over a 6 week period, those supplemented with 5-HTP were able to reduce their carbohydrate intake and experienced a feeling of early satiety, which contributed to significant weight loss. Low levels of serotonin are also associated with sleep problems, low threshold for pain and anxiety.


Many weight loss products work by the same serotonin reuptake inhibiting mechanism, increasing serotonin levels. Beta endorphins seem to fool people into feeling fuller, therefore, individuals eat less and lose weight. If you are unhappy with the results or side effects of your current diet program, 5-HTP may be an effective alternative for you! 5-HTP should not be used with MAO inhibitors or other antidepressants. If unsure, seek professional advice before using 5HTP.


If you want to get a hold of 5 htp the best place that I would recommend is healthyonline and you can go directly to the page here. If you say “Sam sent me” when placing the order they will also give you free shipping and a 5% discount.

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One Comment »

  • lana4 said:

    Thats reall yinteresting to read.I would rather try something like that first as I know overseas countries actualy use natural remedies before the chemicl ones.(St Johns Wort and Glucosamine)Sad our government/medical proffessionals are not for this sort of thing.

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